Matt is a great care giver and he also provides excellent conversation while you’re receiving care, no awkward silence like a typical healthcare visit. I got there right before my appointment and there was no wait time at all he came and saw to me immediately. The overall atmosphere was warm and welcoming. I highly recommend his practice!
Syracuse, NY
By telehealth
Hormone Replacement Therapy for Menopause & Perimenopause in Syracuse, NY
Menopause & Perimenopause HRT by Video · Syracuse & All of New York
Hormone replacement therapy for Syracuse, NY, by telehealth, starting with a full hour on video with a New York-licensed nurse practitioner.
4.9★ Google
66 ★★★★★ reviews
25+ yrs experience
FNP-BC board-certified
Medically reviewed by Matthew Simone, FNP-BC · Last reviewed: November 2, 2026
Matthew, NP · Founder
Matthew Simone, FNP-BC, offers menopause and perimenopause hormone therapy for Syracuse women by telehealth. His office is in Trumansburg, about 1 hour 30 minutes from downtown Syracuse.
Your first visit is a full hour by video. Hot flashes, 3 a.m. waking, brain fog, and mood swings are common, and they are treatable.
Matt builds the plan with you, then follows up by video as it settles in. It is the same approach as our menopause and perimenopause program near Ithaca.
How it works
How telehealth HRT works from Syracuse
Most of your care happens by video, with labs drawn and prescriptions filled near you. Here is what each stage covers, and what stays with your own OB-GYN or primary care provider.
Your one-hour video consultation
Matt starts with your symptoms, such as hot flashes, sleep, mood, and changes in desire or comfort with sex.
He asks about your cycle, including when your periods changed or stopped and any unexpected bleeding.
He reviews your personal and family history for the risks that change which HRT fits you. These include blood clots, breast cancer, stroke or heart disease, and migraine with aura.
Labs, only when they change the plan
Menopause and perimenopause are usually clear from your age and symptoms, so lab work is not needed to make the diagnosis. Even so, Matt runs a comprehensive panel for everyone, because patients want the full picture and other things, such as thyroid or iron, can cause the same symptoms.
That is especially true if you are under 45, or if your symptoms point to another cause.
Matt may check thyroid function, since thyroid problems can look like menopause, or your cholesterol if it has not been checked recently. Labs are drawn at a lab near you.
Starting estrogen and progesterone
Estradiol comes as a patch, gel, or pill. Through the skin, as a patch or gel, it does not raise blood clot risk the way pills do. That matters most if you have clot risk factors or a BMI over 30.
If you still have a uterus, you also take progesterone. Estrogen alone raises the risk of endometrial cancer, and progesterone lowers it. After a hysterectomy, estrogen alone is usually enough. Matt starts one hormone at a time and builds the dose up slowly, so any side effect is easy to spot and adjust.
Estradiol and progesterone are not controlled substances, so Matt can prescribe them by video. Prescriptions go to a pharmacy near you, and are usually covered by insurance.
Testosterone for women
Testosterone may help low sexual desire that causes distress after menopause, when HRT alone has not helped. Its use in women is off-label.
Testosterone is Schedule III, and under current DEA telemedicine rules it can be started by video.
Follow-up by video
Early on, Matt checks in often, usually a quick text every couple of weeks while you dial in your dose, with a more thorough review as needed.
Your first full review is usually about 3 months after you start, to check how well treatment works and any side effects.
After that, you review your plan with Matt once a year, or sooner if symptoms or side effects change.
Your membership works like direct primary care, so between visits you can call or text Matt directly with questions instead of waiting for the next appointment.
If you have a uterus, some bleeding is common in the first 6 months. Tell Matt promptly about bleeding after that.
Screenings and exams
Mammograms, Pap and HPV tests, and pelvic exams stay with your OB-GYN or primary care provider. Hormone therapy does not replace them, so keep them on schedule.
With your permission, Matt shares your plan with them and coordinates if a result changes your treatment.
Sources: NICE guideline NG23, Menopause: identification and management. The Menopause Society, 2022 Hormone Therapy Position Statement. EMAS, Menopause and migraine, 2022. FDA prescribing information for estrogen products, updated Feb 12, 2026. DEA and HHS, Fourth Temporary Extension of COVID-19 Telemedicine Flexibilities, Federal Register, Dec 31, 2025.
Symptoms
Perimenopause and menopause symptoms we treat
Menopause means 12 months in a row without a period. Perimenopause, the years before it, often starts in your 40s, and symptoms can begin while your periods are still coming.
Hot flashes and night sweats
The classic symptoms, often worst at night.
Sleep changes
Waking at 3 a.m. and struggling to get back to sleep.
Mood and focus
Anxiety, irritability, low mood, and brain fog.
Vaginal and urinary symptoms
Dryness, pain with sex, and more urinary urgency.
Body changes
Joint aches and lower libido.
Perimenopause treatment
No need to wait for your periods to stop. Options include hormone therapy and, for some women who still need contraception, low-dose birth control.
A comprehensive panel for everyone. Menopause is usually diagnosed from your age and symptoms, so blood tests are not needed to make the diagnosis. Even so, Matt runs a full panel for everyone, because other things, such as thyroid, can cause the same symptoms.
Go deeper with our posts on perimenopause symptoms with normal labs and whether it is perimenopause or something else. For thyroid causes, see our page on thyroid treatment.
The treatment
What HRT is, and what "bioidentical" means
Menopause hormone therapy replaces some of the hormones your body now makes less of.
Estrogen
Usually estradiol, the main treatment for hot flashes and night sweats.
Progesterone
Added for women who still have a uterus, to protect the uterine lining.
Vaginal estrogen
A low local dose for dryness and urinary symptoms.
FDA-approved bioidentical, not compounded
What "bioidentical" really means
“Bioidentical” means the hormone has the same structure as the one your body makes. FDA-approved bioidentical estradiol and micronized progesterone are widely available by prescription. Compounded “bioidentical” hormones mixed by a pharmacy are not FDA-approved and are not tested the same way. Matt prescribes FDA-approved bioidentical hormones, not compounded ones.
Estrogen comes as a patch, gel, pill, or vaginal cream or tablet, and Matt helps you choose. If estrogen is not right for you, non-hormonal treatments can also help hot flashes and sleep.
Safety
Is HRT safe? What the evidence and the FDA label say
For most healthy women under 60, or within 10 years of menopause, the benefits of hormone therapy for hot flashes and preventing bone loss outweigh the risks. That is the position of The Menopause Society (formerly The North American Menopause Society) in its 2022 statement, which also says treatment should be individualized. Beyond easing symptoms, hormone therapy has longer-term benefits. Estrogen slows the bone loss that speeds up after menopause, which lowers the risk of osteoporosis and fractures. Started within about 10 years of menopause, it may also support heart and metabolic health, with more favorable cholesterol and body-fat patterns. These are reasons to weigh timing and your own history with Matt, not a reason to use hormones only for prevention.
The 2026 label change
On February 12, 2026, the FDA approved the first labeling changes for menopausal hormone therapy products, starting with six. The boxed warning statements about cardiovascular disease, breast cancer, and probable dementia were removed from those labels. The risks remain in Warnings and Precautions, and the boxed warning about endometrial cancer remains for systemic estrogen-alone products.
Timing and your history
Hormone therapy is not used to prevent heart disease or dementia. When you start matters, and Matt reviews your personal and family history first. Systemic HRT generally is not used with a history of certain breast cancers, blood clots, stroke, or active liver disease.
The large Women's Health Initiative trials, first reported in 2002, studied conjugated equine estrogens, with or without medroxyprogesterone acetate, in women whose average age was 63. Today's advice focuses on timing and individual risk.
Testosterone
Testosterone for women: where it fits
A narrow, evidence-based use, prescribed carefully.
What the evidence supports
For postmenopausal women with low sexual desire that causes distress, called hypoactive sexual desire disorder (HSDD), evidence supports a trial of testosterone (Global Consensus Position Statement, Davis, et al., 2019). It does not support use for energy, mood, bone, or heart health.
How it is prescribed
No testosterone product is FDA-approved for women in the US, so any use is off-label, at doses aimed at the normal premenopausal female range. It is also a controlled substance, and under current DEA telemedicine rules it can be started by video.
Our post on testosterone and low libido in women explains the evidence.
Step by step
Your plan, step by step
From your first hour to steady follow-up, mostly by video.
1
One-hour consultation by video
Your history, symptoms, and goals, a clear explanation of your options, and a draft plan ($249).
2
Labs near you, if needed
Drawn at a lab near you, at discounted member rates.
3
Your plan
If you are a good candidate, you can start that day, often at a low dose that builds up gradually.
4
Prescriptions at your pharmacy
Prescriptions go to a pharmacy near you. Insurance or Medicare may cover them.
5
Membership follow-ups
Check-ins, dose adjustments, lab monitoring when appropriate, and direct access to Matt by call or text ($179 a month).
Matthew Simone, FNP-BC
Founder & Family Nurse Practitioner
- FNP-BC, board-certified family nurse practitioner
- 25+ years in healthcare, 19 as a nurse practitioner
- Family practice in the Alaskan bush, plus trauma, emergency, and urgent care
- 2025 NP of the Year, NP Association of New York
- Has served as president of NPA-NY Region 2
- Certified in menopause hormone therapy
Who's caring for you
Your provider: Matthew Simone, FNP-BC
Matthew Simone, FNP-BC, is a board-certified family nurse practitioner, licensed in New York, and the founder of Homesteady Health. He is certified in menopause hormone therapy through the Academy for Advanced Women’s Health Medicine (Heather Hirsch Academy). His 25+ years in healthcare, the last 19 as a nurse practitioner, run from family practice in the Alaskan bush to trauma, emergency, and urgent care.
“I may not be a woman, but I’ve seen firsthand, through friends and family, how hard the perimenopausal and menopausal years can be.”
The Nurse Practitioner Association of New York named him its 2025 Nurse Practitioner of the Year, and he has served as president of its Region 2. The practice holds a 4.9-star rating across 63 Google reviews.
25+
Years in healthcare
19
Years as a Nurse Practitioner
FNP-BC
Board-certified · family practice
NPA·NY
Served as president · Region 2
Patient reviews
What patients say about Matt
4.9
Ratings and reviews from Google Maps
Currently sitting in their parking lot writing this, but I’m a student and had to get tested for TB in order to work a clinical position. I got extremely lost, I called telling them I was lost, and then my phone died leaving me lost for almost an hour. I came in and they were very accommodating, they even still took me in for my appointment. They were very good, gave me a moment to catch my breath, and got me right in there, gave me my test, and set me up for my follow up right away. They were very efficient with great bedside manner; I cannot apologize or thank them enough! Plus they were an absolute life saver for that appointment in the first place because my new job needed a work physical and the test so their same day appointments truly saved me. Thank you again!!!! 100% recommend!!!! Thank you Matt!!!!
Matt is great! He’s thorough and has the time and availability to listen. Just knowing he’s there and you don’t have to go to urgent care because your doctor can’t see you for days gives you peace of mind. Highly recommend.
Pricing
What HRT costs without insurance
No insurance needed to start. Flat, published pricing.
Get started
$249 one time
Initial consultation
- A full hour by video
- Your history and symptoms
- Education on your options
- Your plan
Ongoing care
$179 / month
Hormone membership
- Follow-ups by video
- Dose adjustments
- Lab monitoring when appropriate
- Direct provider access by call or text
| Item | Price | What it covers |
|---|---|---|
| Initial consultation | $249, one time | One hour of history, education, and your plan |
| Hormone membership | $179 a month | Follow-ups, dose adjustments, lab monitoring when appropriate, and direct provider access by call or text |
| Labs | Member rates | Discounted. Insurance can often be used for outside labs |
| Medications | Your pharmacy’s price | Insurance, Medicare, or Medicaid may cover them |
Why is women's care priced differently from men's? The FAQs on our menopause and perimenopause program page explain it.
Syracuse · Finger Lakes
Menopause care in Syracuse, with a Finger Lakes office
Most menopause care is conversation, a plan, and careful adjustments, and all of it works well by video. Your first hour with Matt can happen from home.
When you do come in
The office is about 1 hour 30 minutes from downtown Syracuse, by I-81 and NY 13, then NY 96 through Ithaca. From Skaneateles or Auburn, US 20 and NY 89 along Cayuga Lake take about 1 hour to 1 hour 15 minutes. Parking is free, and labs can be drawn on site.
Winter and screenings
Lake-effect snow can make the drive hard, so many patients use video visits in winter. Routine screenings stay with your own OB-GYN or primary care provider in Syracuse.
Primary care by video too
Want a primary care provider as well? See telehealth primary care for Syracuse. For a partner, see testosterone therapy for Syracuse.
Homesteady Health Direct Primary Care
1859 Trumansburg Road, Trumansburg, NY 14886
- Downtown Syracuse about 1 hr 30 min
- Fayetteville about 1 hr 40 min
- Camillus about 1 hr 25 min
- Skaneateles about 1 hr 15 min
Office hours Monday to Friday, 8am to 5pm. Visits by video across New York. Drive times are off-peak estimates.
Questions · Straight answers
HRT for Syracuse FAQs
Do I have to come to Trumansburg?
Usually not. Visits happen by video, and labs are drawn near home. Estradiol and progesterone can be prescribed by video. Testosterone can be started by video under current DEA telemedicine rules. The office is about 1 hour 30 minutes from downtown Syracuse.
Where do I get labs in Syracuse?
At a lab draw site near you. We send the order, and discounted member pricing applies. Insurance can often be used for outside lab work. Many women do not need labs to start, since menopause is usually diagnosed from age and symptoms.
Can I keep my OB-GYN?
Yes. Keep your OB-GYN or primary care provider for mammograms, Pap and HPV screening, and routine exams. Matt manages your hormone therapy and, with your permission, shares your plan with them.
Bioidentical vs FDA-approved: what is the difference?
“Bioidentical” means the hormone matches the one your body makes. FDA-approved bioidentical estradiol and micronized progesterone are available at regular pharmacies. Compounded bioidentical products are mixed by a pharmacy and are not FDA-approved. Matt prescribes FDA-approved products.
Is HRT safe now that the FDA changed the warning?
On February 12, 2026, the FDA removed boxed warning statements on heart disease, breast cancer, and dementia from the first updated labels. Those risks are still listed. The Menopause Society says benefits generally outweigh risks for most healthy women under 60 or within 10 years of menopause. Matt reviews your history first.
How much does HRT cost without insurance?
A $249 one-hour consultation, then $179 a month for the hormone membership. Insurance is not needed to start. Medications are filled at your pharmacy, where insurance, Medicare, or Medicaid may cover them.
Can perimenopause be treated before my periods stop?
Yes. Symptoms often start years before your last period, and there is no need to wait. Depending on your health and whether you need contraception, options may include hormone therapy or a low-dose birth control pill. Matt talks through what fits.
Who will I see?
Matthew Simone, FNP-BC, a board-certified family nurse practitioner certified in menopause hormone therapy. He is the same provider at every visit, by video from home, with our Trumansburg office for anything that needs to be in person.
You don't have to push through it
One hour by video · published pricing
Menopause care for Syracuse by video, with one New York nurse practitioner and published pricing. Start with an hour that is all about you.